The TFα antigen is found in human cells. TF is a carbohydrate-based antigen first discovered by scientist Thomsen and Friedenreich from the University of Copenhagen. Named after its discoverers, TF refers to the same antigen, with TFα classified
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TF α antigen in normal cell
TFα antigen is present in normal cells, but usually does not appear because it is surrounded by specific carbohydrates.
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Exposing TFα antigen in cancer cells
However, when normal cells transform into cancer cells, structural changes occur in this region, causing the TFα antigen to become exposed on the cell surface.
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TFα antigen-antibody bind
At this time, the TFα antigen on the surface of the cancer cell exposed is recognized in the body, and TFα antibodies are naturally produced and increased. TFα antibodies can bind to the TFα antigen on the surface of the cancer cell.